Dr. Abdulaziz AlRashed — Consultant Dermatologist, Cosmetic & Laser

Oral Antifungal Tablets (Terbinafine / Itraconazole)

A patient advice sheet — 8 practical points. Reviewed and updated by Dr. Abdulaziz AlRashed, July 2026.

Last reviewed: July 2026

The advice

  1. Antifungal tablets are the effective treatment for nail and scalp fungus and widespread infections; creams alone are not enough for these.
  2. Usual terbinafine duration: 6 weeks for fingernails, 12 weeks for toenails — daily without interruption.
  3. A liver test is done before starting (and may be repeated as needed); stop the drug and tell us immediately for: persistent nausea, loss of appetite, dark urine, jaundice, or unusual fatigue.
  4. Terbinafine can temporarily alter taste — tell us if it happens.
  5. Itraconazole interacts with many medicines (some cholesterol, heart and allergy drugs) — tell us all your medicines before starting; it is taken after food.
  6. Keep alcohol at zero during the course, and treatment is usually deferred in pregnancy.
  7. Very important: the nail still looks bad after successful treatment until a completely new nail grows out (12–18 months for toenails) — this does not mean failure.
  8. Prevent reinfection: apply the hygiene sheet (thorough drying, cotton socks, antifungal spray inside shoes, your own tools).

See also the full treatment page: Nail fungus treatment — options, evidence and expected timelines.

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