Dr. Abdulaziz AlRashed — Consultant Dermatologist, Cosmetic & Laser

Advice for Patients on Roaccutane (Isotretinoin)

Last reviewed 1 July 2026 — Dr. Abdulaziz AlRashed

A patient advice sheet — 9 practical points. Reviewed and updated by Dr. Abdulaziz AlRashed, July 2026.

Last reviewed: July 2026

The advice

Dryness is the most common side effect: apply lip balm several times daily, moisturize face and body, use lubricating eye drops, and Vaseline inside the nose for dryness or nosebleeds.
Use sunscreen daily — the drug makes your skin more sun-sensitive.
For married women: pregnancy is absolutely forbidden during treatment and for one full month after the last dose; use two contraception methods together, with monthly pregnancy tests.
Do not donate blood during treatment and for one month after stopping.
Blood tests (liver enzymes & lipids): before starting, then after about 2 months at a stable dose, as directed — current guidelines no longer require monthly testing for most patients.
Limit fast food, fried food and red meat — the drug can raise triglycerides.
Avoid waxing, laser hair removal, chemical peels and cosmetic procedures during treatment and for 6 months after, unless approved by your doctor.
Do not take vitamin A supplements; report any unusual mood change immediately.
Treatment usually lasts 4–6 months depending on severity and response.

See also the full treatment page: Acne treatment — options, evidence and expected timelines.

My private clinic at Kuwait Hospital (Sabah Al-Salem) — direct assessment and a treatment plan built around your case.